Publicaciones/Publications - R.DeograciasLab

Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits. Deogracias R*, Favuzzi E*, Marques-Smith A, Maeso P, Jezequel J, Exposito-Alonso D, Balia M , Kroon T, Hinojosa AJ, Maraver EF, Rico B. *Equal contribution. Science. 2019.
The Microtubule Regulator NEK7 Coordinates the Wiring of Cortical Parvalbumin Interneurons. Hinojosa AJ, Deogracias R, Rico B. Cell Reports. 2018
Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican. Favuzzi E, Deogracias R*, Marques-Smith A*, Winterflood CM, Sánchez-Aguilera A, Mantoan L, Maeso P, Fernandes C, Ewers H, Rico B. *Equal contribution. Neuron. 2017.
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome. Deogracias R*, Yazdani M*, Dekkers MP, Guy J, Ionescu MC, Vogt KE, Barde YA. *Equal contribution. PNAS. 2012.
Seizure-induced neuronal death is suppressed in the absence of the endogenous lectin Galectin1. Deogracias R*, Bischoff V, Poirier F, Barde Y-A. *Equal contribution. J Neurosci. 2012.
Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons. Deogracias R*, Yazdani M*, Guy J, Poot RA, Bird A, Barde Y-A. *Equal contribution. Stem Cells. 2012.
Topoisomerase IIβ binding to promoters in postmitotic cells modulates gene activity and regulates neuronal survival. Tiwari W, Burger L#, Nikoletopoulou V#, Deogracias R, Wirbelauer C, Murr R, Terranova R, Mielke. C, Boege F, Lyu Y-L, Peters A, Barde Y-A, Schübeler D. *Equal contribution. PNAS. 2012.
BDNF and its pro-peptide are stored in presynaptic large dense core vesicles in brain neurons. Dieni S, Matsumoto T, Dekkers M, Rauskolb S, Ionescu M, Deogracias R, Gundelfinger E-D, Kojima M, Nestel S, Frotscher M, Barde Y-A. The Journal of Cell Biology. 2012.
Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity. Vidaurre O-G#, Gascón S#, Deogracias R, Sobrado M, Cuadrado E, Montaner J, Rodríguez-Peña A, and M. Díaz-Guerra. #Equal contribution. Cell Death and Disease. 2012.
Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. Rauskolb S, Zagrebelsky M, Dreznjak A, Deogracias R, Matsumoto T, Wiese S, Erne B, Sendtner M, Schaeren-Wiemers, Korte M and Barde Y-A. J Neurosci. 2010.
Transcription of the NR1 subunit of the N-methyl-D-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia. Gascon S, Deogracias R, Sobrado M, Roda JM, Renart J, Rodriguez-Pena A, Diaz-Guerra M. The Journal of Biological Chemistry. 2005.
Expression of the neurotrophin receptor TrkB is regulated by the cAMP/CREB pathway in neurons. Deogracias R, Espliguero G, Iglesias T and Rodriguez-Pena A. Molecular and Cellular Neuroscience. 2004.